Clozapine-Induced Febrile Neutropenia and Cellulitis

Selcuk YAYLACI; Emine Ulku YILMAZ; Ertugrul GUCLU; Neslihan AKKISI KUMSAR; Ali TAMER; Oguz KARABAY

doi:10.5505/1304.7361.2014.83097

Selcuk YAYLACI¹, Emine Ulku YILMAZ¹, Ertugrul GUCLU², Neslihan AKKISI KUMSAR³, Ali TAMER¹, Oguz KARABAY²

¹Department of Internal Medicine, Sakarya University Faculty of Medicine, Sakarya
²Department of Infectious Diseases and Clinical Microbiology, Sakarya University Faculty of Medicine, Sakarya
³Department of Physiciatry, Sakarya University Faculty of Medicine, Sakarya

Keywords: Cellulitis; clozapine; febrile neutropenia; granulocyte colonystimulating factor

Abstract

Clozapine is one of the atypical antipsychotics and is frequently prescribed to patients with treatment-resistant schizophrenia. Agranulocytosis is a major side effect that may lead to death, which limits its use. This is a case report of a patient that developed febrile neutropenia and cellulitis after treatment with clozapine for 20 weeks.