In vitro fertilization‑induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review
Nguyen Huu Thanh1
, Trinh Van Duong1, Nguyen Thu Huyen2, Pham Dang Hai2
1College of Health Sciences, VinUniversity, Ha Noi, Vietnam
2Medical Intensive Care Unit, 108 Military Central Hospital, Ha Noi, Vietnam
Keywords: Acute pancreatitis, estrogen, hypertriglyceride, in vitro fertilization
Abstract
Acute pancreatitis is one of the severe complications of hypertriglyceridemia, which needs to be recognized early to provide appropriate treatment. Hypertriglyceridemia induced pancreatitis has several causes, in which in vitro fertilization (IVF) is a rare etiology that is becoming increasingly popular. We report a 33 year old female patient with a history of hypertension who has failed an IVF cycle and started a new IVF procedure 1 month before admission. She was diagnosed with severe triglyceridemia induced acute pancreatitis with extremely high serum triglycerides (TGs) levels (18,547 mg/dL). We combined plasmapheresis and intravenous (IV) insulin and significantly reduced blood TG over a short time. She was discharged with a TG level of 366.7 mg/dL on the 10th day. It is essential to monitor serum TG levels in plasma before, during, and after this therapy, especially in the 1st month after initiating IVF. Although plasmapheresis combined with IV insulin is not officially recommended for acute triglyceridemia induced pancreatitis, the therapy can be considered in cases with extremely high serum TG levels.
How to cite this article: Thanh NH, Duong TV, Huyen NT, Hai PD. In vitro fertilization-induced extreme hypertriglyceridemia with secondary acute pancreatitis in emergency department: A case report and literature review. Turk J Emerg Med 2024;24(4):255-8.
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Conceptualization (Pham Dang Hai, Nguyen Huu Thanh); writing – original draft (Nguyen Huu Thanh, Trinh Van Duong, Nguyen Thu Huyen); writing – review and editing (Pham Dang Hai). All the authors read and approved the final manuscript.
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