Messenger ribonucleic acid vaccine‑associated immune thrombocytopenia: A rare complication of vaccine

Mehmet Sami Islamoglu; Mehmet Dokur; Betul Borku Uysal; Mehmet Gunduz

doi:10.4103/2452-2473.342810

Mehmet Sami Islamoglu¹, Mehmet Dokur², Betul Borku Uysal¹, Mehmet Gunduz³

¹Department of Internal Medicine, Biruni University Medical Faculty, Istanbul, Turkey
²Department of Emergency Medicine, Biruni University Medical Faculty, Istanbul, Turkey
³Department of Hematology, Biruni University Medical Faculty, Istanbul, Turkey

Keywords: COVID 19, COVID 19 Vaccines, Coronavirus disease‑2019 vaccine, immune thrombocytopenia, purpura, severe acute respiratory coronavirus‑2, SARS-CoV-2 Infection

Abstract

Coronavirus disease 2019 continues to have a serious impact in countries with the effect of new variant viruses emerging with mutations. While the effectiveness and protection of the vaccine have been determined all over the world, some vaccine related side effects can be detected in the form of cases. In our case, the patient was admitted to the emergency department of our hospital with complaints of weakness and progressive rash on his legs. Diffuse petechiae purpura on the legs of the patient was observed and complete blood count revealed thrombocytopenia. Peripheral blood smear supported the blood count test results with thrombocytopenia, secondary causes of thrombocytopenia were excluded, and the patient was diagnosed with vaccine induced immune thrombocytopenia.