A successful treatment with intravenous lipid emulsion therapy in a child with verapamil poisoning
Merve Havan1*, Tanıl Kendirli1, Serhan Özcan1, Melih Timuçin Doğan2, Ahmet Onur Yiğit1, Tayfun Uçar2
1Department of Pediatric Intensive Care, School of Medicine, Ankara University, Ankara, Turkey
2Department of Pediatric Cardiology, School of Medicine, Ankara University, Ankara, Turkey
Keywords: Children, intoxication, lipid emulsion therapy, verapamil
Abstract
In recent years, intravenous lipid emulsion therapy (ILE) was used for lipophilic drug intoxications, and successful results were obtained. In the literature, there is a small number of reported cases about verapamil intoxication and ILE therapy in the pediatric age group. We used ILE therapy in a 14-year-old girl with verapamil intoxication in the 2nd h of the pediatric intensive care unit stay, before using traditional treatments such as glucagon and hyperinsulinemic euglycemia. She had resistant bradycardia and hypotension which was unresponsive to inotropic agents and a successful result was obtained after using ILE treatment. We believe our report may contribute to the early use of ILE therapy for toxicity with calcium channel blockers such as verapamil in pediatric patients.
The authors certify that they have obtained all appropriate patient consent forms. In the form, the parents have given their consent for images and other clinical information to be reported in the journal. The parents understand that names and initials will not be published, and due efforts will be made to conceal identity, but anonymity cannot be guaranteed.
Merve Havan: Conceptualization (lead); writing – original draft (lead); Methodology (lead). Tanıl Kendirli: Supervision (lead); Visualization (lead). Serhan Özcan: Methodology (lead); Resources; Writing – original draft (supporting). Melih T. Doğan: Resources (supporting). Onur Yiğit: Resources Writing – original draft (supporting). Tayfun Uçar: Writing – review and editing (equal).
None Declared.
None.
In this case report everyone who contributed to this manuscript is listed as an author.