The relationship between trauma scores and blood C-reactive protein, lactate and creatinine kinase levels in blunt trauma patients

Abstract

Objectives: The aim of this study was to compare the relationship between trauma scores and blood creatinine kinase, C-reactive protein and lactate levels in blunt trauma patients in the emergency department.
Materials and Methods: The study was performed prospective in 60 adult patients (age>16 years) brought to the emergency department due to blunt injury between the dates of 1 January 2002 and 1 March 2003. Patients was first evaluated in respect of injury severity score; then 30 patients having injury severity score higher than or equal to 25 were included in the study as study group, 30 patient having injury severity score lower than 25 were included in the study as control group. Additionally, their Glasgow Coma Scale scores were calculated. Blood samples were taken from the patients at the arrival, 6th and 12th hours to evaluate blood creatinine kinase, Creactive protein, and lactate levels.
Results: The twelfth hour blood C-reactive protein and lactate level on arrival of the patients group having injury severity score higher than 25 were significantly higher than the other group (p<0.05). In both of the groups there was no relation between creatinine kinase levels and injury severity scores. There was a positive correlation between C-reactive protein and injury severity score at 12th hour. Also there was positive correlation between lactate levels and injury severity scores on arrival.
Conclusion: Although there was no positive relationship between biochemical parameters and trauma scoring systems, when they are used together they may be helpful in the estimation of the prognosis.